She made the leap to adult roles with “Lost in Translation”, opposite Bill Murray, for which she was nominated for a Golden Globe and won a BAFTA. She followed the performance with “The Girl With the Pearl Earring”, for which she was again nominated for both a Golden Globe and a BAFTA. In 2004 she had five film releases: “The Perfect Score,” “A Love Song for Bobby Long,” “A Good Woman,” the live-action animated comedy “The SpongeBob SquarePants Movie,” and “In Good Company.”
She began working with director Woody Allen in 2005 with the drama “Match Point.” They continued to work together on “Scoop” (2006) and “Vicky Cristina Barcelona” (2008), for which she was nominated for an Academy Award for Best Supporting Actress. In 2010, she appeared opposite Robert Downey, Jr in Iron Man 2 as the anti-heroine Black Widow. That would be the beginning of her long-term relationship with the Marvel Cinematic Universe (MCU). She has since reprised her role as Black Widow in “The Avengers” (2012), “Captain America: The Winter Soldier” (2014), “Avengers: Age of Ultron” (2015), “Captain America: Civil War” (2016), and “Avengers: Infinity War” (2018), among other MCU films.
Other notable films she has appeared in include “The Black Dahlia” (2006), “The Other Boleyn Girl” (2008), “Lucy” (2014), “Marriage Story” (2019), and “Jojo Rabbit” (2019). She has also voiced characters in “Her” (2013), “The Jungle Book” (2016), “Isle of Dogs” (2018), and “Sing 2” (2021). She’s playing the role of Midge Campbell in 2023’s “Asteroid City” and has other projects in the works.