Larson was cast in the 2001 sitcom Raising Dad and 2004 comedy Sleepover. The actress starred in the Disney Channel original movie Right on Track (2003). Larson garnered attention for characterizing Kate in the Showtime’s breakout drama United States of Tara (2009).
She landed the lead role in the independent drama Short term 12 (2013), which was her breakthrough role. Larson characterized the kidnapping victim in the 2015 drama Room, for which she won the Academy Award for Best Actress.
Her most notable works include the Marvel cinematic universe superhero films Captain Marvel and Avengers: Endgame; she played the character of Carol Danvers. Some of her successful films include 21 Jump Street (2012), Don Jon (2013), Spectacular Now (2013), Trainwreck (2015), Kong: Skull Island (2017), etc.
Larson made her directorial debut with the 2017 Independent comedy-drama Unicorn Store. The actress bagged a Primetime Emmy Award for the production of the 2020 virtual reality series Messy Truth VR Experience. The actress also explored her musical talent as she released her album Finally Out of PE in 2005.